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  Indian J Med Microbiol
 

Figure 2 The c-KIT receptor is a transmembrane protein (CD 117). The receptor is divided into an extra-cellular domain, a trans-membrane domain, and an intra-cellular tail. The intra-cellular part is further divided into a juxta-membrane domain and a tyrosine kinase domain. Different types of GISTs have different mutations expressing changes in different parts of the transmembrane receptor protein.

Figure 2 The c-KIT receptor is a transmembrane protein (CD 117). The receptor is divided into an extra-cellular domain, a trans-membrane domain, and an intra-cellular tail. The intra-cellular part is further divided into a juxta-membrane domain and a tyrosine kinase domain. Different types of GISTs have different mutations expressing changes in different parts of the transmembrane receptor protein.