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Year : 2019  |  Volume : 5  |  Issue : 1  |  Page : 24-28

Ampullary Neuroendocrine Tumor With Multiple Gastrointestinal Stromal Tumors in a Patient with Von Recklinghausen’s Disease Patient: A Case Report

1 Department of Pathology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
2 Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, Phulwari Shari, Patna, India
3 Department of Pathology, All Institute of Medical Sciences, Phulwari Shari, Patna, India

Correspondence Address:
Dr. Rakesh Kumar Gupta
Department of Pathology, Academic Block, All India Institute of Medical Sciences, Raipur, Tatibandh - 492099
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mamcjms.mamcjms_51_18

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Von Recklinghausen’s disease (VRD) is a hereditary disease that occurs because of mutation in NF1 gene located on chromosome 17. About 25% of VRD patients are reported to suffer from gastrointestinal lesions varying from hyperplasia of the gut neural tissue, endocrine tumors of the duodenum and the periampullary region, and gastrointestinal stromal tumors. Herein, we describe a case of ampullary neuroendocrine tumor with unique histology and immunohistochemistry in a 35-year-old male patient with VRD, detailed review of literature.

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